Consensus conference on the management of tumor lysis syndrome
نویسندگان
چکیده
منابع مشابه
Consensus conference on the management of tumor lysis syndrome.
Tumor lysis syndrome is a potentially life threatening complication of massive cellular lysis in cancers. Identification of high-risk patients and early recognition of the syndrome is crucial in the institution of appropriate treatments. Drugs that act on the metabolic pathway of uric acid to allantoin, like allopurinol or rasburicase, are effective for prophylaxis and treatment of tumor lysis ...
متن کاملManagement of pediatric tumor lysis syndrome.
INTRODUCTION Tumor lysis syndrome (TLS) is a serious complication of malignancies and can result in renal failure or death. REVIEW In tumors with a high proliferative rate with a relatively large mass and a high sensitivity to cytotoxic agents, the initiation of therapy often results in the rapid release of intracellular anions, cations and the metabolic products of proteins and nucleic acids...
متن کاملThe tumor lysis syndrome.
From the Department of Oncology and International Outreach Program, St. Jude Children’s Research Hospital (S.C.H., C.-H.P.), and the Department of Pediatrics, University of Tennessee Health Sciences Center, College of Medicine (S.C.H., D.P.J., C.-H.P.) — both in Memphis. Address reprint requests to Dr. Howard at St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Barry-Longinotti Bld...
متن کاملThe Efficacy of Single Dose Rasburicase in Prevention or Treatment of Tumor Lysis Syndrome in Children
Background: Tumor lysis syndrome (TLS) is a major metabolic complication in patients with malignancy after initiation of chemotherapy or spontaneously without treatment. The role of Rasburicase (a recombinant urate-oxidase enzyme) in prevention and treatment of TLS has been demonstrated in recent years. We aimed to investigate the efficacy of a single dose of rasburicase in reducing the risk of...
متن کاملThe Prevalence of Tumor Lysis Syndrome in Children and Adolescents with Cancer in Hamedan Province, Iran
Background: Tumor lysis syndrome caused by widespread tumor cell damage may lead to electrolyte imbalances and express as metabolic disturbance causing clinical abnormalities. Patients and Methods: All patients younger than 16 years with documented malignancy candidate for chemotherapy, in Hamedan province of Iran were enrolled. Results: Out of 69 cancer patients the laboratory form of tumor ...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2008
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.13290